NFL Week 16 odds, predictions: Picks, lines, spreads for every game

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National Football League

Updated
Dec. 23, 2023 5:11 p.m. ET

The NFL playoff picture is starting to come into focus as a few teams have been eliminated while others are jockeying for position as we head into Week 16.

Football fans are looking forward to watching games on four days this week – one on Thursday night, two on Saturday, 10 on Christmas Eve and three on Christmas.

A huge showdown between the Dallas Cowboys and Miami Dolphins on Christmas Eve on FOX Sports and the FOX Sports App highlights the slate.

Another key contest between division leaders Baltimore Ravens and San Francisco 49ers should be a fun one, and it is the final game of the week on Christmas Day.

When it comes to betting, here’s everything you need to know about the NFL odds for Week 16 — the point spread, moneyline and total Over/Under.

All times ET

THURSDAY’S GAME

Saints @ Rams (8:15 p.m., Amazon Prime Video)

Point spread: Rams -4 (Rams favored to win by more than 4 points, otherwise Saints cover)Moneyline: Rams -198 favorites to win (bet $10 to win $15.05 total); Saints +163 underdogs to win (bet $10 to win $26.30 total)Total scoring Over/Under: 44.5 points scored by both teams combined

New Orleans Saints

NO

Los Angeles Rams

LAR

SATURDAY’S GAMES

Bengals @ Steelers (4:30 p.m., NBC)

Point spread: Steelers -1 (Steelers favored to win by more than 1 point, otherwise Bengals cover)Moneyline: Steelers -116 favorites to win (bet $10 to win $18.62 total); Bengals -104 underdogs to win (bet $10 to win $19.62 total)Total scoring Over/Under: 39.5 points scored by both teams combined

Cincinnati Bengals

CIN

Pittsburgh Steelers

PIT

Bills @ Chargers (8 p.m., Peacock)

Point spread: Bills -12 (Bills favored to win by more than 12 points, otherwise Chargers cover)Moneyline: Bills -772 favorites to win (bet $10 to win $11.30 total); Chargers +538 underdogs to win (bet $10 to win $63.80 total)Total scoring Over/Under: 44 points scored by both teams combined

Buffalo Bills

BUF

Los Angeles Chargers

LAC

Dave Helman’s NFL Coaching Spotlight features Carolina’s Chris Tabor

RELATED: NFL Week 15 top viral moments

SUNDAY’S GAMES

Colts @ Falcons (1 p.m., FOX and FOX Sports App)

Point spread: Falcons -2.5 (Falcons favored to win by more than 2.5 points, otherwise Colts cover)Moneyline: Falcons -143 favorites to win (bet $10 to win $16.99 total); Colts +119 underdogs to win (bet $10 to win $21.90 total)Total scoring Over/Under: 45.5 points scored by both teams combined

Indianapolis Colts

IND

Atlanta Falcons

ATL

Lions @ Vikings (1 p.m., FOX and FOX Sports App)

Point spread: Lions -3 (Lions favored to win by more than 3 points, otherwise Vikings cover)Moneyline: Lions -158 favorites to win (bet $10 to win $16.33 total); Vikings +134 underdogs to win (bet $10 to win $23.40 total)Total scoring Over/Under: 47.5 points scored by both teams combined

Detroit Lions

DET

Minnesota Vikings

MIN

Packers @ Panthers (1 p.m., FOX and FOX Sports App)

Point spread: Packers -4 (Packers favored to win by more than 4 points, otherwise Panthers cover)Moneyline: Packers -209 favorites to win (bet $10 to win $14.78 total); Panthers +173 underdogs to win (bet $10 to win $27.30 total)Total scoring Over/Under: 37.5 points scored by both teams combined

Green Bay Packers

GB

Carolina Panthers

CAR

Seahawks @ Titans (1 p.m., CBS)

Point spread: Seahawks -3.5 (Seahawks favored to win by more than 3.5 points, otherwise Titans cover)Moneyline: Seahawks -174 favorites to win (bet $10 to win $15.75 total); Titans +146 underdogs to win (bet $10 to win $24.60 total)Total scoring Over/Under: 41.5 points scored by both teams combined

Seattle Seahawks

SEA

Tennessee Titans

TEN

Commanders @ Jets (1 p.m., CBS)

Point spread: Jets -3 (Jets favored to win by more than 3 points, otherwise Commanders cover)Moneyline: Jets -164 favorites to win (bet $10 to win $16.10 total); Commanders +138 underdogs to win (bet $10 to win $23.80 total)Total scoring Over/Under: 37 points scored by both teams combined

Washington Commanders

WAS

New York Jets

NYJ

Browns @ Texans (1 p.m., CBS)

Point spread: Browns -3 (Browns favored to win by more than 3 points, otherwise Texans cover)Moneyline: Browns -156 favorites to win (bet $10 to win $16.41 total); Texans +130 underdogs to win (bet $10 to win $23 total)Total scoring Over/Under: 40 points scored by both teams combined

Cleveland Browns

CLE

Houston Texans

HOU

Jaguars @ Buccaneers (4:05 p.m., CBS)

Point spread: Jaguars -1 (Jaguars favored to win by more than 1 point, otherwise Buccaneers cover)Moneyline: Jaguars -119 favorites to win (bet $10 to win $18.40 total); Buccaneers -102 underdogs to win (bet $10 to win $19.80 total)Total scoring Over/Under: 43 points scored by both teams combined

Jacksonville Jaguars

JAX

Tampa Bay Buccaneers

TB

Cardinals @ Bears (4:25 p.m., FOX and FOX Sports App)

Point spread: Bears -4 (Bears favored to win by more than 4 points, otherwise Cardinals cover)Moneyline: Bears -205 favorites to win (bet $10 to win $14.80 total); Cardinals +170 underdogs to win (bet $10 to win $27 total)Total scoring Over/Under: 43 points scored by both teams combined

Arizona Cardinals

ARI

Chicago Bears

CHI

Cowboys @ Dolphins (4:25 p.m., FOX and FOX Sports App)

Point spread: Dolphins -1.5 (Cowboys favored to win by more than 1.5 points, otherwise Dolphins cover)Moneyline: Dolphins -128 favorites to win (bet $10 to win $17.81 total); Dolphins +107 underdogs to win (bet $10 to win $20.70 total)Total scoring Over/Under: 49.5 points scored by both teams combined

Dallas Cowboys

DAL

Miami Dolphins

MIA

Patriots @ Broncos (8:15 p.m., NFL Network)

Point spread: Broncos -7 (Broncos favored to win by more than 7 points, otherwise Patriots cover)Moneyline: Broncos -353 favorites to win (bet $10 to win $12.83 total); Patriots +279 underdogs to win (bet $10 to win $37.90 total)Total scoring Over/Under: 35 points scored by both teams combined

New England Patriots

NE

Denver Broncos

DEN

MONDAY’S GAMES

Raiders @ Chiefs (1 p.m., CBS)

Point spread: Chiefs -10.5 (Chiefs favored to win by more than 10.5 points, otherwise Raiders cover)Moneyline: Chiefs -562 favorites to win (bet $10 to win $11.78 total); Raiders +411 underdogs to win (bet $10 to win $51.10 total)Total scoring Over/Under: 40.5 points scored by both teams combined

Las Vegas Raiders

LV

Kansas City Chiefs

KC

Giants @ Eagles (4:30 p.m., FOX and FOX Sports App)

Point spread: Eagles -13.5 (Eagles favored to win by more than 13.5 points, otherwise Giants cover)Moneyline: Eagles -802 favorites to win (bet $10 to win $11.25 total); Giants +538 underdogs to win (bet $10 to win $63.80 total)Total scoring Over/Under: 43 points scored by both teams combined

New York Giants

NYG

Philadelphia Eagles

PHI

Ravens @ 49ers (8:15 p.m., ABC/ESPN+)

Point spread: 49ers -6 (49ers favored to win by more than 6 points, otherwise Ravens cover)Moneyline: 49ers -259 favorites to win (bet $10 to win $13.86 total); Ravens +208 underdogs to win (bet $10 to win $30.80 total)Total scoring Over/Under: 47 points scored by both teams combined

Baltimore Ravens

BAL

San Francisco 49ers

SF

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